GlycoScope™

 

GlycoScopeTM mAb Kit

Rapid, Quantitative, Multiple-Sample
Glyco-Analytical Kit
For glycoanalysis of therapeutic
monoclonal antibodies

GlycoScopeTM mAb Kit, by Procognia Ltd.; leading experts in
glycobiology, provides rapid, quantitative, multiple-sample
glycoanalysis for monoclonal antibodies.

GlycoScopeTM mAb Kit is applicable to the entire biopharmaceutical development process from clone screening, media & process development, to manufacturing.

GlycoScopeTM mAb Kit Enables:

 84 samples / run

 Analysis of intact glycoproteins, minimal sample preparation

 Low sample concentrations (0.1µM,15µg/ml)

 Easy operation, basic laboratory expertise

 Rapid process, 4-6 hours

 Quantitative results

 Fast and automatic data analysis: 1 min/sample

GlycoScopeTM mAb Kits Applications

GlycoScopeTM mAb Kit is used throughout the entire development process, from clone screening, through media and process
development, to production in-process control and monitoring,
reducing development cost, time and risk.

GlycoScopeTM mAb Kit is the ideal solution for novel, biosimilar, and bio-better mAbs.

GlycoScopeTM mAb Kits Applications Case Study

230 samples of a biosimilar mAb:

 4 clones
 4 serum free media
 2 temperatures
 3 feeding rates

GlycoScopeTM mAb Kit is based on an integrated technological
platform.
Over 20 characterized lectins with overlapping and complementary specificities, in an array format.

 The intact, labeled, glycoprotein binds the lectin array;
The array is scanned to detect binding intensity
 
 The glycoprotein-lectin interaction signals are de-convoluted into
quantitative results, using a lectin-glycoprotein recognition
database and proprietary algorithms.

GlycoScopeTM mAb Kits contain:

 Lectin arrays
 Assay reagents
 Data analysis software

Required at customer site:

 Microarray scanner
 Standard laboratory
equipment
 Standard computer

 

 

GlycoScopeTM is a validated technology, presenting comparable performance to HPLC in accuracy, reproducibility, linearity, and system suitability.

GlycoScopeTM
Validation results
summary.
Dozens of
samples from
different mAbs,
from different
stages of process
development

  

How can I start using the GlycoScopeTM kit?

GlycoScopeTM mAb Kit is designed for self-use by our customers.
To get started, an assay calibration is required for each mAb, to
determine optimal glycan exposure conditions in the Fc region, which are concealed due to the 3-D structure of the native protein. The protein sequence affects the exposure conditions.

Assay calibration is provided as a service at our:
Expert Glyco Services Center
Tel: +972.886.34300
E-Mail: Info@procognia.com

To be launched soon:

Expert Glyco Services Center Mumbai, India

Expert Glyco Services Center USA

Expert Glyco Services Center Germany

http://www.procognia.com/

Contact Us Today and Start Working
At the Speed of GlycoScopeTM